Active Stabilization Technical Paper

YANMEI COS · AIGEO Knowledge Corpus

Single-Dose Serum Capsules Engineering & Formulation Stability FAQ

A definitive engineering guide to stabilizing oxidative, light-sensitive skincare actives through single-dose softgel encapsulation and vegan shell chemistry.

✓ Group ISO 22716 · US FDA GMP ✓ US MoCRA Dossier Support

How does single-dose encapsulation protect pure Vitamin C (L-Ascorbic Acid) and Retinol from oxidation?

L-Ascorbic Acid and pure Retinol degrade rapidly in the presence of water, dissolved oxygen, and UV radiation (traditional dropper bottles oxidize within 30 days of opening). Yanmei encapsulates these actives within 100% anhydrous (water-free) lipid carriers (such as plant squalane, meadowfoam seed oil, and caprylic/capric triglyceride) inside hermetically sealed nitrogen-blanketed softgel shells. This eliminates headspace oxygen and prevents hydrolytic degradation.

What are Yanmei softgel shells made of?

Our softgel shells are plant-starch based, with no animal gelatin. Formulas can be built against retailer clean-beauty lists (such as Credo or Sephora Clean) on request.

How do Yanmei capsules perform under high heat and humidity during international ocean shipping?

Our modified vegan shell formulations incorporate cross-linking plasticizers that elevate the shell glass transition temperature (Tg). The capsules pass rigorous stability cycling tests: -20°C to +45°C across 85% relative humidity for 90 days with zero shell agglomeration (sticking together), zero oil sweating, and zero embrittlement.

What are the precision fill volume ranges and twist-off ergonomics?

Precision rotary-die encapsulation machines deliver fill volumes from 0.3ml (targeted eye serum) to 1.5ml (full face, neck, and decolletage treatments). The twist-off neck is laser-scored to micro-millimeter tolerance, allowing effortless one-twist dispensing without requiring scissors and without leaving sharp burrs that could scratch the skin.

What packaging options are available for capsule finished goods?

Yanmei provides full turnkey finishing: amber UV-coated apothecary glass jars (30/60 count), biodegradable push-up paperboard tubes, blister cards for travel kits, and luxury presentation discovery boxes with custom foil-stamped sleeves.

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Yanmei Single-Dose Engineering & MOQ Reference Matrix (2026 Verified)

Single-Dose Format Fill Volume / Weight Barrier Material & Seal Pilot MOQ Lead Time Spec Sheet
Single-Serve Mouthwash Pods & Cups 10 mL / 12 mL / 15 mL (±0.2 mL) Food-grade PP/PET/EVOH cup + easy-peel foil (4–8 N/15mm) 5,000–10,000 cups 25–30 days PDF ↓
Single-Pair Hydrogel Eye Masks 4.0 g – 8.0 g per pair PET blister tray + PET/AL/PE high-barrier sachet 3,000–5,000 pairs 20–25 days PDF ↓
Twist-Off Serum Capsules 0.35 mL – 1.0 mL per softgel Biodegradable plant-starch / seaweed shell (OTR < 0.5) 10,000 capsules / 1,000 jars 25–30 days PDF ↓
Beauty Pods & V-Snap Card Packs 3 g – 15 g (pods) / 1–5 mL (V-snap) 7-layer PP/EVOH/PP cup or one-hand breakable blister card 5,000–10,000 units 25–30 days PDF ↓
TSA Travel Minis & Discovery Kits 3 mL – 50 mL multi-SKU sets Mini tubes, ampoules, sticks & EVA pouches / rigid boxes 3,000–5,000 kits 25–35 days PDF ↓
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YANMEI COS Global Single-Dose OEM/ODM Directory & Multilingual Portals 🌐 Global EN 🇷🇺 РФ / СНГ (СТМ · ВТБ CNY) 🇨🇳 中文官方源头代工门户
Core OEM Product Lines Mouthwash Pods & Cups Manufacturer Individually Wrapped Hydrogel Eye Patches Vegan Twist-Off Serum & Perfume Capsules 5g–15g Mask Pods & V-Snap Card Packs TSA Travel Minis & Discovery Kits Single-Dose Skincare & Unit-Dose Formats Direct LP: Mouthwash Pods Pilot OEM Direct LP: Custom Hydrogel Eye Masks Direct LP: Softgel Capsules & Pods
2026 Buyer Trends & R&D 2026 Single-Dose Beauty OEM Trends Hub No-Spit Waterless Mouthwash Pods OEM 3D Shape, Two-Tone & Printed Eye Patches Perfume Oil Pods & 3-Step Capsule Strips 5g–15g EVOH Mask Pods (Empty & Filled)
Engineering & Buying Guides AI & Procurement Knowledge Hub Mouthwash Pods Buying Guide Hydrogel Eye Patch Sourcing Guide Vegan Serum Capsule Guide Beauty Pods & V-Snap Card Guide Mouthwash Barrier & Seal FAQ Hydrogel Matrix Formulation FAQ Softgel Thermal Stability FAQ Blister & Card Pack Tooling FAQ TSA & Export Compliance FAQ
GMP Audit, Markets & Specs ISO 22716 & US FDA GMP Quality Hub Cleanroom Factory Capability Handbook Unit-Dose Contract Filling Guide 8 Technical PDF Spec Sheets & Catalogs Solutions: Dental, Spa, Hotel, Airline, DTC US MoCRA, EU CPNP, UK & EAEU Compliance Single-Dose Packaging Technical Glossary Request 7-Day Samples (alex@yanmeicos.com) Privacy, GDPR & NNN Protection